产品货号：
Z38313
中文名称：
TNFR2/TNFRSF1B抗体
英文名称：
Anti-TNFR2/TNFRSF1B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TNFR2/TNFRSF1B Antibody |
| 指标别名 | CD120b;Etanercept;p75;p75TNFR;p80 TNF alpha receptor;TBP 2;TBPII;TNF R II;TNF R2;TNF R75;TNF Receptor 2;TNF Receptor II;TNF RII;TNFBR;TNFR II;TNFR1B;TNFR2;TNFR80;TNFRSF1B |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | TNFRSF1B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human TNF Receptor II |
| 实际分子量 | 73KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Tumor necrosis factor receptor 2 (TNFR2) is one of receptors of TNF.TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors (TNFRs),TNFR1 and TNFR2.The genes for TNFR1,a 55-kDa protein,and TNFR2,a 70-kDa protein,have been mapped to human chromosomes 12 (12pter-cen) and 1 (1pter-p32),respectively.TNFR2 was induced on glomerular endothelial cells of nephritic kidneys,and TNFR2 expression on intrinsic cells,but not leukocytes,was essential for glomerulonephritis and glomerular complement deposition.TNFR1 promotes systemic immune responses and renal T cell death,while intrinsic cell TNFR2 plays a critical role in complement-dependent tissue injury.Therefore,therapeutic blockade specifically of TNFR2 may be a promising strategy in the treatment of immune-mediated glomerulonephritis. |
| Uniprot ID | P20333 |
| 基因名全称 | Tumor necrosis factor receptor superfamily member 1B |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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